Spatiotemporal Behavior of High Dominant Frequency During Paroxysmal and Persistent Atrial Fibrillation in the Human Left Atrium
نویسندگان
چکیده
منابع مشابه
Mechanisms of fractionated electrograms formation in the posterior left atrium during paroxysmal atrial fibrillation in humans.
OBJECTIVES The aim of this paper was to study mechanisms of formation of fractionated electrograms on the posterior left atrial wall (PLAW) in human paroxysmal atrial fibrillation (AF). BACKGROUND The mechanisms responsible for complex fractionated atrial electrogram formation during AF are poorly understood. METHODS In 24 patients, we induced sustained AF by pacing from a pulmonary vein. W...
متن کاملDominant frequency increase rate predicts transition from paroxysmal to long-term persistent atrial fibrillation.
BACKGROUND Little is known about the mechanisms underlying the transition from paroxysmal to persistent atrial fibrillation (AF). In an ovine model of long-standing persistent AF we tested the hypothesis that the rate of electric and structural remodeling, assessed by dominant frequency (DF) changes, determines the time at which AF becomes persistent. METHODS AND RESULTS Self-sustained AF was...
متن کاملLong-term frequency gradients during persistent atrial fibrillation in sheep are associated with stable sources in the left atrium.
BACKGROUND Dominant frequencies (DFs) of activation are higher in the atria of patients with persistent than paroxysmal atrial fibrillation (AF), and left atrial (LA)-to-right atrial (RA) DF gradients have been identified in both. However, whether such gradients are maintained as long-term persistent AF is established remains unexplored. We aimed at determining in vivo the time course in atrial...
متن کاملAblation of Paroxysmal and Persistent Atrial Fibrillation
Introduction Atrial fibrillation (AF) is the most common arrhythmia in humans. Its maintenance is thought to be due to multiple wavelets reentry occurring in both atria [1]. Previous studies have demonstrated the feasibility and efficacy of cryoablation to create lesions in both atria [2] and on the posterior wall of the left atrium [3], connecting the four pulmonary veins and the mitral annulu...
متن کاملEffect of adenosine triphosphate on left atrial electrogram interval and dominant frequency in human atrial fibrillation.
BACKGROUND Complex fractionated atrial electrograms (CFAEs) and high dominant frequency (DF) are targets for atrial fibrillation (AF) ablation. Although adenosine triphosphate (ATP) is known to promote AF by shortening the atrial refractory period, its role in the pathogenesis of CFAEs and DF during AF is not fully understood. METHODS We recorded electrical activity from a 64-electrode basket...
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ژورنال
عنوان ژورنال: Circulation: Arrhythmia and Electrophysiology
سال: 2012
ISSN: 1941-3149,1941-3084
DOI: 10.1161/circep.111.967992